Obestatin induced recovery of myocardial dysfunction in type 1 diabetic rats: underlying mechanisms
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چکیده
منابع مشابه
Obestatin induced recovery of myocardial dysfunction in type 1 diabetic rats: underlying mechanisms
BACKGROUND The aim of this study was to investigate whether obestatin (OB), a peptide mediator encoded by the ghrelin gene exerting a protective effect in ischemic reperfused heart, is able to reduce cardiac dysfunctions in adult diabetic rats. METHODS Diabetes was induced by STZ injection (50 mg/kg) in Wistar rats (DM). OB was administered (25 μg/kg) twice a day for 6 weeks. Non-diabetic (ND...
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Type 1 diabetes is a chronic disease characterized by the body's inability to produce insulin due to destruction of the beta cells. There is increasing evidence that reactive oxygen species (ROS) play a major role in the development of diabetic complications. The purpose of this study is to investigate the effects of troxerutin administration on oxidative stress markers in blood of STZ-induced ...
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ژورنال
عنوان ژورنال: Cardiovascular Diabetology
سال: 2012
ISSN: 1475-2840
DOI: 10.1186/1475-2840-11-129